The Eagles compiled a 2-1 record in the three-game series.
Cowan allowed only one hit in five shutout innings, with five strikeouts and two walks.
Kirkwood scored eight runs in the second inning and owned a 16-3 lead after seven frames. Cuyahoga tallied six times in the eighth inning to make the score more respectable.
Jamarion Loston went 3-for-5 with a double and three RBIs for the Eagles. Taylor Jackson was 2-for-4 with two doubles and scored three runs. Zion Pettigrew was 2-for-5 and scored twice. Kam Arons had two RBIs. Levi Usher and D'Eric Shenault scored twice.
Kirkwood 082 002 400 - 16 12 2
Cuyahoga 000 003 060 - 9 9 x
Cowan, Llewellyn (6), Frese (7), Elion (8), Hews (8), Day (8) and Vaske. W - Cowan (1-0).